Top Stocks, Crypto Moves, and Market Drivers: March 2025 Update

As of March 25, 2025, the U.S. stock market and cryptocurrency sectors have experienced a dynamic start to the year, shaped by technological innovation, macroeconomic shifts, and evolving regulatory landscapes. 

See Update: Top Stocks and Crypto: April 2025 Update

The stock market has seen resilience in certain sectors despite volatility, while cryptocurrencies continue to capture attention with significant price movements. Companies in technology, biotechnology, and energy solutions—such as TSS, Inc., Monopar Therapeutics, and Vistra Corp.—are among those driving stock market narratives, while Bitcoin (BTC) and XRP lead the charge in the digital asset space. This article examines the performance of key stocks and cryptocurrencies year-to-date (YTD), alongside emerging trends influencing the financial landscape. Meanwhile, gold and silver ETFs have gained traction as safe-haven assets amid market uncertainty.


U.S. Stock Market Overview

The U.S. stock market has shown resilience amid recent economic concerns:

  • Dow Jones Industrial Average: Gained nearly 600 points on March 24, 2025, driven by optimism over tariff adjustments. (WSJ)

  • S&P 500 and Nasdaq Composite: Both indices finished higher despite weaker consumer confidence data, indicating underlying market strength. (MarketWatch)

Investor sentiment remains cautiously optimistic as markets respond to evolving trade policies and economic indicators.


Cryptocurrency Market Update

The cryptocurrency market has maintained its upward trajectory into 2025, bolstered by institutional adoption and policy shifts, though recent fluctuations highlight ongoing risks.
  • Bitcoin (BTC)
    • YTD Trend: Significant gains, with volatility.
    • Key Driver: Institutional investment and Bitcoin ETF inflows.
    • Bitcoin started 2025 strong, building on its late-2024 surge past $100,000. As of March 25, its price has fluctuated around $87,000-$90,000 following a dip earlier this month, influenced by macroeconomic concerns and policy announcements. The establishment of a U.S. strategic Bitcoin reserve, announced in early March, initially sparked enthusiasm, though the lack of immediate purchase plans tempered some bullish sentiment.
  • XRP – Steady Utility Growth
    • YTD Trend: Consistent upward movement.
    • Key Driver: Use in cross-border payments and DeFi.
    • XRP has seen steady gains in 2025, with its price hovering around $2.00-$2.10 as of March 25. Its adoption by financial institutions for efficient global transactions continues to underpin its value, though it remains sensitive to regulatory developments.


Gold and Silver ETFs: Safe-Haven Assets Gain Interest

With growing economic uncertainty, gold and silver ETFs have attracted increased investment as safe-haven assets:

Top Gold ETFs in 2025

  • SPDR Gold Shares (GLD) – One of the largest gold ETFs, offering direct exposure to gold prices.

  • iShares Gold Trust (IAU) – A lower-cost alternative to GLD with strong liquidity.

  • VanEck Gold Miners ETF (GDX) – Tracks gold mining stocks, offering indirect exposure to gold prices.

  • iShares Gold Trust Micro (IAUM) - IAUM has a one-year return of 34.80% and boasts a low expense ratio of 0.09%.

Gold prices have remained strong in 2025, hovering around $2,500 per ounce, as investors seek protection against inflation and economic downturn risks.

Top Silver ETFs in 2025

  • iShares Silver Trust (SLV) – Provides direct exposure to silver prices, a top choice for silver investors.

  • Aberdeen Standard Physical Silver Shares ETF (SIVR) – Offers a cost-effective alternative to SLV.

Gold prices are holding steady around $2,500 per ounce, while silver trades above $30 per ounce, reflecting their roles as hedges against inflation and economic downturns.


US Stocks with the Best Yearly Performance

Below are some of the standout performers shaping the investment landscape this year.


TSS, Inc. (TSSI)

Sector: Technology / Infrastructure
Stock Growth: +1,852% (1-Year Performance) 
Market Cap: $210M USD
Profile: TSS, Inc. provides integration technology services to implement, operate, and maintain information technology systems to enterprises and users in the United States. The company operates in two segments, Facilities and Systems Integration. It offers a single source solution for enabling technologies in data centers, operations centers, network facilities, server rooms, security operations centers, communications facilities, and the infrastructure systems. The company also provides technology consulting, design and engineering, project management, systems integration, system installation, facilities management, and IT procurement services. It serves IT OEM equipment, technology, and service companies; private sector businesses; and government or commercial end users. The company was formerly known as Fortress International Group, Inc. and changed its name to TSS, Inc. in June 2013. TSS, Inc. was incorporated in 2004 and is headquartered in Round Rock, Texas.

Top Institutional Holders:
  • Vanguard Group Inc.
  • BlackRock Inc.
  • Value Aligned Research Advisors, LLC
  • Evernest Financial Advisors, LLC
  • Geode Capital Management, LLC
  • Mesirow Financial Investment Management, Inc.
  • New York State Common Retirement Fund
  • Palisades Investment Partners, LLC
  • Murchinson Ltd.
  • Citadel Advisors LLC


GeneDx (WGS) – Leading the Charge in Genomics

Sector: Biotechnology / Genomics
Stock Growth: +1,070% (1-Year Performance)
Market Cap: $2.93B USD
Key Driver: Growth in precision medicine and genetic research.
GeneDx continues to dominate the genomics and personalized medicine industry by delivering cutting-edge genetic-based therapies. As demand for customized healthcare solutions rises, GeneDx is emerging as a top biotech stock for 2025.

Top Institutional Holders:

  • BlackRock Inc.
  • Vanguard Group Inc.
  • Summit Partners Public Asset Management LLC
  • William Blair Investment Management, LLC
  • Lord, Abbett & Co. LLC
  • Fred Alger Management, LLC
  • Goldman Sachs Group Inc.
  • Oracle Investment Management Inc.
  • Casdin Capital, LLC
  • Corvex Management LP

AST SpaceMobile Inc. (ASTS) – Revolutionising Satellite Communications

Sector: Telecommunications / Space Technology
Stock Growth: +938% (1-Year Performance)
Market Cap: $8.8B USD
Key Driver: Expansion of satellite-based broadband connectivity and partnerships with major telecom providers. AST SpaceMobile is redefining global communications by developing direct-to-device satellite technology, reducing reliance on traditional cell towers. As demand for uninterrupted connectivity grows, ASTS remains a leading space-tech investment in 2025.

Top Institutional Holders:
  • Vanguard Group Inc.
  • BlackRock Inc.
  • Shaw D.E. & Co., Inc.
  • Broad Run Investment Management, LLC
  • Janus Henderson Group PLC
  • Geode Capital Management, LLC
  • State Street Corporation
  • Morgan Stanley
  • T. Rowe Price Investment Management, Inc.

Diginex Limited (DGNX) – A Rising ESG Player

Sector: Environmental, social, and governance (ESG) solution
Stock Growth: +2,176% (1-Year Performance)
Market Cap: $2.53B USD
Profile: Diginex Limited, through its subsidiaries, engages in the provision of environmental, social, and governance (ESG) reporting solution services, advisory services, and developing customization solutions in Hong Kong, the United Kingdom, and the United States. Its suite of products includes: 

  • digninexESG, a cloud based ESG platform that offers end to end reporting from topic discovery, data collection, and collaborative report publishing services;
  • diginexLUMEN that allows companies to execute supply chain risk assessments; diginexAPPRISE, a multilingual application that collects standardized, actionable data related to working conditions directly from workers in supply chains;
  • diginexCLIMATE, a carbon footprint calculator based on the GHG protocols;
  • diginexADVISORY that provides clients strategy and advisory support for credible reporting; diginexPARTNERS that develops white label versions of diginexESG and diginexLUMEN; and diginexMANAGEDSERVICES that provides oversight and support to clients.

The company was founded in 2020 and is headquartered in Telegraph Bay, Hong Kong.

Major Shareholders:
  • Rhino Ventures Ltd. 
  • Hearst Corp. /Venture Capital/ 
  • Nalimz Holdings Ltd. 
  • Natalia Pelham 
  • Miles Pelham 
  • Mark Blick 
  • Christian Thierfelder 
  • Graham Bridges 

Palantir Technologies Inc. (PLTR) – AI-Powered Data Analytics

Sector: Technology / Big Data & AI
Stock Growth: +300% (1-Year Performance)
Market Cap: $48.2B USD
Key Driver: Rising adoption of AI-driven data analysis in government, defense, and enterprise applications.
Palantir has solidified its position as a leader in data intelligence and AI-driven analytics, providing critical insights to governments and Fortune 500 companies. With the increasing demand for predictive analytics and AI-enhanced security, PLTR remains a key tech stock to watch in 2025.

Top Institutional Holders:
  • Vanguard Group Inc.
  • BlackRock Inc.
  • ARK Investment Management LLC
  • Morgan Stanley
  • State Street Corporation

Power Solutions International Inc. (PSIX) – Innovating Clean Energy

Sector: Energy / Industrial Equipment
Stock Growth: +1,459% (1-Year Performance)
Market Cap: $629M USD
Profile: Power Solutions International, Inc. designs, engineers, manufactures, markets, and sells engines and power systems in the United States, North America, the Pacific Rim, Europe, and internationally. The company offers engine blocks integrated with fuel system parts, as well as completely packaged power systems, that include combinations of front accessory drives, cooling systems, electronic systems, air intake systems, fuel systems, housings, power takeoff systems, exhaust systems, hydraulic systems, enclosures, brackets, hoses, tubes, packaging, telematics, and other assembled componentry. It also designs and manufactures large, custom-engineered integrated electrical power generation systems for standby and prime power applications. In addition, it provides mobile and stationary gensets for emergency standby, rental, prime power, demand response, microgrid, oil and gas, data center, renewable energy resiliency, and combined heat and power; forklifts, wood chippers, stump grinders, sweepers/industrial scrubbers, aerial lift platforms/scissor lifts, irrigation pumps, oil and gas compression, oil lifts, off road utility vehicles, ground support equipment, ice resurfacing equipment, pump jacks, and battery packs; and vocational trucks and vans school buses, transit buses, and terminal and utility tractors. Power Solutions International, Inc. was founded in 1985 and is headquartered in Wood Dale, Illinois. Power Solutions International, Inc. is a subsidiary of Weichai America Corp.


Monopar Therapeutics Inc. (MNPR) – Biotech on the Rise

Sector: Healthcare / Biotechnology
Stock Growth: +1,023% (1-Year Performance)
Market Cap: $176M USD
Key Driver: Advances in oncology treatments and a favorable biotech investment climate.
Monopar Therapeutics is making strides in cancer treatment research, with strong momentum in clinical trials and biotech funding. Its innovative approach to oncology has made it a standout biotech stock in early 2025.


Best Growth Stocks for AI, Biotech, and Clean Energy – 2025

As markets remain volatile, investors looking for long-term growth opportunities should focus on high-potential sectors like Artificial Intelligence (AI), biotechnology, and clean energy. These industries are expected to drive innovation and deliver strong returns in the coming years.

Stock Market Insights
  • AI Dominance: AI-related stocks remain market leaders as adoption expands across industries.
  • Biotech Breakthroughs: Companies like GeneDx and Monopar Therapeutics are at the forefront of healthcare transformation.
  • Energy Surge: The energy sector thrives amid AI and crypto-driven demand.
  • Financial Evolution: Traditional finance integrates AI and blockchain, enhancing resilience.

Top AI Stocks in 2025

AI continues to dominate market growth, fueled by advances in machine learning, automation, and AI-driven applications. 

 

Best AI Stocks: 

 

✅ Nvidia (NVDA) – The leader in AI chips, powering machine learning and data centers.

✅ AMD (AMD) – A top competitor in AI semiconductors and high-performance computing.
✅ Palantir (PLTR) – Provides AI-powered data analytics for government and enterprise solutions.
✅ Alphabet (GOOGL) – Google’s AI-driven initiatives in search, cloud, and automation continue to expand.
✅ C3.ai (AI) – A pure-play AI company offering enterprise AI software solutions. 

 


Investment Strategy:
📌 Focus on AI chipmakers (NVDA, AMD) for core exposure.
📌 Add AI software firms (PLTR, C3.ai) for diversification.




Top Biotech Stocks in 2025

Biotech stocks are benefiting from gene editing, personalized medicine, and AI-driven drug discovery

 


Best Biotech Stocks: 

 


✅ Vertex Pharmaceuticals (VRTX) – Specializing in rare genetic disease treatments.
✅ Genedx (WGS) – A top player in genomic medicine and personalized healthcare. 

 


Investment Strategy:
📌 Invest in gene-editing pioneers (CRSP, VRTX) for long-term growth.




Top Clean Energy Stocks in 2025

Clean energy stocks are rising due to global decarbonization efforts, EV expansion, and green energy policies

 


Best Clean Energy Stocks:

✅ Tesla (TSLA) – The dominant leader in EVs and battery storage technology.
✅ Enphase Energy (ENPH) – Specializing in solar microinverters and renewable energy solutions.
✅ NextEra Energy (NEE) – A top U.S. renewable energy provider.
✅ Brookfield Renewable Partners (BEP) – Global leader in hydro, wind, and solar energy.
✅ Power Solutions International (PSIX) – Developing alternative fuel powertrain solutions. 

 


Investment Strategy:
📌 EV stocks (TSLA, PSIX) offer long-term potential as electric mobility expands.
📌 Renewable energy leaders (NEE, BEP, ENPH) provide steady growth and dividends.




Final Thoughts & Portfolio Strategy for 2025

As AI, biotech, clean energy, satellite technology, and blockchain drive market trends, these stocks represent some of the top investment opportunities for 2025.

Investors should build a diversified portfolio to balance risk and capture growth:

📌 35% AI & Tech Stocks – Nvidia, AMD, Palantir, C3.ai, TSSI, PDYN
📌 20% Biotech & Healthcare – CRISPR, Vertex, GeneDx, MNPR
📌 15% Clean Energy – Tesla, Enphase, PSIX
📌 15% Safe-Haven Assets – Gold & Silver ETFs for stability

📌 

15% Crypto & Blockchain - Bitcoin (BTC), XRP (XRP)

By balancing investments in high-growth sectors while hedging with precious metals, investors can position themselves for long-term success in 2025.


Investment Strategies for 2025: General

With market volatility remaining high, investors should consider diversified investment strategies to protect their portfolios and maximize gains.

1. Diversification Across Asset Classes

✅ Invest in a mix of stocks, cryptocurrencies, and precious metals to reduce risk.
✅ Consider gold and silver ETFs as hedges against inflation and economic downturns.
✅ Maintain exposure to growth sectors like AI, biotech, and clean energy.

2. Focus on Defensive Stocks & Dividend Payers
✅ Defensive sectors such as utilities, healthcare, and consumer staples tend to perform well during uncertainty.
✅ Dividend-paying stocks provide passive income and help offset market downturns.

3. Tactical Crypto Investment Strategy

✅ Use dollar-cost averaging (DCA) to minimize risk in volatile crypto markets.
✅ Allocate only a small portion (5-10%) of your portfolio to crypto for balanced exposure.
✅ Watch for Bitcoin price movements near support levels ($70,000 - $80,000) before making large investments.

4. Precious Metals for Stability

✅ Allocate 5-15% of your portfolio to gold and silver ETFs as safe-haven assets.
✅ Consider mining stocks (GDX, SIL) for indirect exposure and potential upside.

5. Monitor Economic Policies & Interest Rates

✅ Stay updated on Federal Reserve interest rate decisions that could impact markets.
✅ Watch for potential tariffs or economic policies that might affect specific sectors.


Key Takeaways for Investors

  • Stock Market Uncertainty: Investors remain cautious amid high valuations, inflation concerns, and trade risks.
  • Crypto Volatility: Bitcoin and altcoins have faced sharp corrections, requiring a strategic investment approach.
  • Gold & Silver Demand: Precious metals and gold/silver ETFs are becoming attractive hedging tools.
  • Diversification is Key: A balanced portfolio across stocks, crypto, and safe-haven assets can help navigate 2025’s challenges.

Smart Investment Strategies: When to Buy, Hold, or Sell in a Volatile Market

Q: Should I buy now?

A: The decision to buy depends on market conditions and your current holdings:

  • If the price is high, consider selling some shares if you hold a significant amount.

  • If the price is low, it may be a good opportunity to buy, especially if you have little exposure.

  • Follow the "buy the dip, sell the rip" strategy but ensure you're not chasing unsustainable momentum.

  • If the price falls below your support level (e.g., 200-day simple moving average (SMA)), avoid buying more to limit downside risk.

  • For beginners, a long-term approach is often safer. Prioritize fundamental strength over short-term price movements.

  • If the price closes below your support level, consider exiting your position to manage risk.


Q: If the price is high or trending up, should I buy?

A:

  • If you have low exposure, adding to your position during pullbacks can be a strategic move.

  • If you already hold a sizable position, consider selling a portion if it exceeds your portfolio allocation.

  • Holding is a viable option unless you urgently need liquidity.

  • Avoid FOMO (Fear of Missing Out)—buying at all-time highs without a clear strategy can be risky.


Q: If the price is trending down, should I sell?

A:

  • If the price falls below key support levels (e.g., 200-day moving average (DMA) or exponential moving average (EMA)), it might signal further downside.
  • Consider closing positions if technical indicators confirm a bearish trend to minimize losses.
  • If you're a long-term investor, ensure the fundamentals remain strong before making a decision.

What’s Next for Investors?

As of March 25, 2025, the U.S. stock and cryptocurrency markets exhibit a blend of opportunity and caution. The stock market’s tech and energy sectors show resilience, though broader indices have faced pressure from tariff announcements and inflation fears. Cryptocurrencies, while volatile, benefit from institutional interest and policy tailwinds, such as the U.S. Bitcoin reserve initiative. Investors should remain vigilant, balancing these trends with potential risks like geopolitical tensions or monetary policy shifts. The remainder of 2025 will likely hinge on how these dynamics evolve, with AI, energy, and digital assets at the forefront.

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