Povidone Iodine, Oral and Nasal Hygiene 2022

-

Everyone is familiar with nasal and oral swab testing for COVID-19. It should be obvious the virus is replicating in the nose, and with Omicron, the speed of replication has become much greater than the prior strains of the virus. Thus, there is a wonderful opportunity to reduce viral replication, in fact, kill viruses with agents directly applied in the nasal cavity and the back of the throat. This article is not meant to undermine official guides but to provide additional under-rated evidence for you to decide.

Use of directly applied therapy is far more effective than swallowing pills or capsules or receiving an intravenous infusion. The nasal mucosa is a barrier for entry and if functioning well, allows little penetration of virions into systemic circulation where for example a monoclonal antibody could work. 

Many have asked which solutions, mixtures, and frequencies should be used?

One should be reassured that is far more important to use some form of nasal and oral topical therapy as opposed to letting the infection take its course and ultimately invade the lungs and the internal organs.

For purposes of this stack, we acknowledge that many can be effective including: 
  • povidone-iodine,
  • hydrogen peroxide,
  • colloidal silver,
  • xylitol,
and for the throat many mouthwashes including
  • Scope and
  • Listerine.
Principles are:

1) nasal solutions should be comfortable and not sting with sufficient dilution,

2) sniffed far back into the sinuses and then spit out through the mouth (often causes coughing or mild choking), done at least twice per nostril per session,

3) oral gargles should be for 30 seconds and then spit out. For detailed descriptions of products and solutions please visit one of several websites to get this practical information. (R)

Oropharyngeal viricidal therapy has been demonstrated in supportive studies and randomized trials to:

1) prevent infection after suspected exposure (twice daily),

2) reduce the period of infectivity when ill, and

3) attenuate the progression of disease and reduce the need for oxygenation and hospitalization (six times daily).


Povidone Iodine

10% Povidone Iodine is available OTC (Over the Counter) without a prescription at any drug store for a few dollars. Here is the link: Povidone 10% Iodine on Amazon

Note: This 10% Povidone Iodine must be diluted by one tenth, to 1% strength before use as a mouth wash, otherwise it is too strong and irritating. Dilute by adding 2 tablespoons (30 ml) of the 10% Povidone Iodine into a full glass of water (250-300 ml). This will make the product diluted enough to use as a mouth rinse, or gargle, (approximately 1.0 %).

2 tablespoons = 30ml povidone iodine
1 glass water = 300 ml

Povidone iodine (PVP-I) is an antiseptic that has been used for over 150 years. The antiseptic has immediate virucidal effects against COVID-19 virus. Do we have any evidence that povidone iodine is effective against COVID-19? 

There are 20 published studies supporting povidone-iodine for COVID-19. You can check out the list below (c19pvpi.com).



Povidone-iodine is ranked no. 4 in this COVID-19 early treatment mortality drug league table below. However, this is based on only 1 study.



In a December 4th, 2021 interview with Rebel News, Peter McCullough MD discusses what is known about the Omicron variant, and the use of Povidone Iodine Mouthwash, Povidone Iodine Nasal Antiseptic Wash and Gargle for prevention of Covid-19. Dr. McCullough cites the Choudhury study in which 606 COVID infected patients were randomized to 1% povidone iodine, or saline placebo mouthwash and gargle. Patients were followed with PCR testing for viral load. 

Dr. Iqbal Mahmud Choudhury conducted a protocol in Bangladesh that used a povidone-iodine rinse in the nose, mouth, and eyes to kill the virus. Dr. Choudhury writes:

The group of patients used 1% PVP-I [One per cent Povidone Iodine Solution] have shown tremendously reduced mortality, morbidity and hospital as well as financial burden in this covid situation.

A study by Avinash Bidra found complete inactivation of the virus after 15 seconds of gargling with a 1% Povidone Iodine Solution. According to the authors, Povidone Iodine (1%) solution is “rapidly virucidal” at all dilutions tested.

A reader (Drew458) commented on Naked Capitalism:

My favorite paper is this one from some ENTs in Bangladesh, who diluted common 10% PVP to 0.6% and made it up by the gallon in soda bottles, poured it into plastic sprayers and gave it to hundreds of their patients as a nasal and throat spray. Great pictures. It worked. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026810/


Is it Safe to use Iodine in a nasal rinse?

Povidone-iodine can safely be used in the nose at concentrations up to 1.25% and in the mouth at concentrations up to 2.5% for up to 5 months. Povidone-iodine rapidly inactivates coronaviruses, including SARS and MERS, when applied for as little as 15 seconds.


Related: Simple Nasal Wash Reduces Risk of COVID Hospitalization (Ear, Nose & Throat journal in August 2022)


Povidone Iodine vs Iodine

Despite having similar sounding names, iodine and povidone-iodine are two different compounds and a distinct difference can be noted between these two compounds based on their composition and uses.

Iodine is a pure element, and it contains 100% iodine in its composition. It is found in solid form, grayish black small crystals with a metallic luster. Iodine can be obtained in all three forms; solid, liquid and gas. Liquid iodine is a dark purple colored solution, and iodine gas (I2) is a purple colored gas. 

Povidone-iodine is a complex of iodine and povidone. It has from 9%-12% of iodine on the dry basis. (source)

Pregnancy Warning:

From Betadine Drug Facts - If pregnant, ask a health professional before use.
Editor's Note - Use should be limited for a short period i.e. no more than 5 days according to FLCCC I-MASK+ protocol. Caution is recommended as the therapeutic benefit must be balanced against the possible effects of the absorption of iodine on thyroid development and function.

    Online Shopping Guide:
    • 10% Povidone Iodine: 

    mouthwash for COVID-19

    Related: 

    Z-Dtox Supplement 

    z-dtox zelenko
    Dr. Vladimir Zelenko’s groundbreaking work on the immune system has led to this exciting breakthrough.

    Your immune system can be weakened by over 300 different primary immunodeficiency disorders, poor diet, lack of sleep, and adverse reactions to various vaccines.

    That’s where Z-DTOX comes in! Z-Dtox is Dr. Zelenko’s proprietary combination of NAC, EGCG, Zinc, Vitamin C, and Vitamin D.

    Ingredients:
    • Epigallocatechin gallate (EGCG) is an extract of green tea and is a powerful zinc Ionophore (zinc delivery system).
    • N-acetyl cysteine (NAC) is a supplement form of cysteine. It may prevent blood clots and is an antioxidant.
    • Zinc is critical for immune cell development. Dozens of different enzymes in the body rely on zinc.
    • Vitamin C is an essential nutrient involved in the repair of tissue and the enzymatic production of certain neurotransmitters.
    • Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and many other biological effects.
    Z-Dtox is more powerful than Z-Stack. It has EGCG instead of Quercetin, NAC, and higher dose Zinc. It is more appropriate for higher risk patients. For example, those people that have a dysfunctional immune system, risk of blood clots, older people and those with chronic medical conditions.

    Z-Dtox also has 60 servings per container instead of 30 servings per container for Z-Stack.

    Where to buy Z-Dtox: Z-Dtox is available on Dr Zelenko's website. Here is the link: Z Dtox Supplement 

    Note: To get 5% OFF, please use this coupon code: DRFRANCIS

    Comments

    Post a Comment

    Pages

    Popular posts from this blog

    Best 6 Retirement Villages in Malaysia 2024

    -
    Image
    Are you thinking of finding the best retirement home  for your parents in Malaysia? The demand for retirement homes in Malaysia can only go up in view of the increasing number of senior citizens in need of retirement homes that are affordable with good quality related support services. Malaysia is one of the top 10 retirement destinations in the world, based on the  Annual Global Retirement Index for the year 2020 .  Malaysian cities are clean and modern, its public transport unrivalled, and its people the friendliest in Asia. And while other Asian countries offer great budget holidays, and some offer first-class vacations, Malaysia manages to cater extraordinarily well to both. Next, you may need to understand some of the retirement related jargons here. There are many related terms such as retirement village, retirement home, retirement resorts, old folks homes, nursing homes, dual-key etc. So that we are on the same page, let's stick to the terms as defined by the Malaysian Mini
    Read more

    Glutathione vs NAD: What's the Difference?

    -
    Image
    What's the difference between glutathione and NAD? We will cover the essentials and explain about each of these nutrients below.  What is Glutathione? Glutathione or GSH (tripeptide of glutamic acid, cysteine, and glycine) is referred to as the body’s “master antioxidant” or the “mother of all antioxidants” because it is your body’s primary and most prevalent protector, found in all mammalian tissue. Types of Glutathione There is a lot of confusion about GSH and what makes an effective glutathione supplement. There are different types, different formulas, and a lot of different companies saying different things. L-Glutathione or Reduced Glutathione because it is the most commonly found, least expensive, and the true core behind other forms you will find. There is some debate whether L-Glutathione alone can be effective taken orally. The theory being the enzymes in your stomach break it down before it can ever reach the blood stream and become useful. Some  evidence  suggests using
    Read more

    6 Best Cloud Kitchens in Kuala Lumpur and Selangor 2024

    -
    Image
    If you are looking for the best cloud kitchens in Malaysia, you've come to the right place. Like seemingly everything else, technology has been taking over the food industry. Traditionally, around  60% of new restaurants fail  within the first year, and almost 80% shut down before their fifth anniversary.  What are cloud kitchens (a.k.a. ghost kitchens, shared kitchens, dark kitchens or virtual kitchens)? They have been  in the news  a lot lately. So chances are that you have at least heard of them. On the surface, cloud kitchens are delivery-only restaurants.  Historically in tech, we have used the word "cloud" to mean either that the web-based processing happens at some remote data center or the files are saved at a data center. However, the meaning of the word has evolved lately to include anything that happens remotely so you can get the final product wherever you are. Cloud kitchens are restaurants that only have kitchens. They are essentially food production facilit
    Read more

    6 Best NMN Supplements To Buy In 2024

    -
    Image
    NMN is one of the most popular supplements in the anti aging community. The global Nicotinamide Mononucleotide (NMN) market was valued at US$ 98.5 million in 2019 and it is expected to reach US$ 296.5 million ( R ) by the end of 2026, growing at a CAGR (Compound Annual Growth Rate) of 7.3% during 2021-2026. NMN is the precursor to NAD, which our cells use to power metabolic activity. In other words, NAD is essential for our cells to generate energy and thrive. By middle age, our NAD levels have plummeted to half that of our youth. And this decline has been linked to various age-related diseases. The hope is that NMN, being the direct precursor to NAD, can boost levels and extend longevity. What actually is NMN? NMN is short for Nicotinamide mononucleotide and it's the precursor to NAD (Nicotinamide adenine dinucleotide). In fact, two NMN molecules combined together make NAD. But NMN is actually one of many intermediary molecules before the fo
    Read more

    12 Best SME Business Loans in Malaysia 2024

    -
    Image
    SME or also known as Small and Medium-sized Enterprises are businesses that maintain revenues, assets, or a number of employees below a certain threshold. These business entities are often regarded as the heartbeat of Malaysia’s emerging and developing economies. Apart from providing vast numbers of employment opportunities, SME businesses are generally entrepreneurial in nature, helping to shape innovation. Generally, there are two criteria to be met in order for your business to qualify as an SME -- your annual sales turnover and the number of full time employees in your company. This also implies differently for each economy sector: Manufacturing (Small SMEs) Sales turnover RM300,000 to < RM15 million Full time employees 5 to < 75 people Manufacturing (Medium SMEs) Sales turnover RM15 million to < RM50 million Full time employees 75 to < 200 people Services & Others   (Small SMEs) Sales turnover RM300,000 to < RM3 million Full time employees 5 to < 30 people Se
    Read more

    Estate Planning in Malaysia: Importance, Process, Will vs Trust, and Challenging a Will

    -
    Image
    Estate planning is the process of preparing for the management and distribution of one's assets and properties upon death or incapacity. In Malaysia, estate planning is crucial to avoid legal issues and disputes among family members and beneficiaries. In this article, we will discuss the importance of estate planning in Malaysia, the estate planning process, will vs trust in Malaysia, and how to challenge a will in Malaysia. Why is Estate Planning Important in Malaysia? Without proper estate planning, the distribution of a deceased's assets and properties will be governed by the Distribution Act 1958 or the Islamic Family Law (Federal Territories) Act 1984 (applicable to Muslims). These laws may not necessarily reflect the deceased's wishes or the family's needs, causing disputes and legal battles among the beneficiaries. Moreover, estate planning can help reduce the burden of taxes and administrative costs on the beneficiaries. Proper planning can minimize or eliminate
    Read more

    FLCCC I-Care Early Treatment Protocol (2023)

    -
    Image
    The Front Line COVID-19 Critical Care (FLCCC) Alliance was initially formed as a working group under “emergency” conditions of the early COVID-19 pandemic in response to multiple early reports of COVID patients with an inexplicably high need for prolonged mechanical ventilation and an excessive mortality associated with the prevailing “supportive care only” recommendations disseminated by the majority of national and international health care organizations. Early treatment is critical and the most important factor in managing this disease. COVID-19 is a clinical diagnosis; a confirmed antigen or PCR test is not required. Treatment should be initiated immediately after the onset of flu-like symptoms. The multiple therapies and drugs in this protocol have different mechanisms of action and work synergistically during various phases of the disease. About this Protocol The information in this document is our recommended approach to COVID-19 based on the best (and most recent) literature. I
    Read more

    10 Best E Wallets in Malaysia 2024

    -
    Image
    An e-wallet is a feature within an app that allows transactions to be made via a smartphone. Similar to a traditional 'wallet', the e-wallet stores digital cash instead of physical cash. The prominence of e-wallets in Malaysia has grown significantly in the past few years, with its huge growth mainly driven by the government’s efforts and active marketing efforts by various companies. Credit: CompareHero.my Let’s check out the popular eWallets in Malaysia now with their payment method, top up method and other features as below: 1) E Wallet Touch 'n GO Courtesy of tngdigital.com.my TouchnGO eWallet is owned by TNG Digital Sdn Bhd, It’s an all in one e-wallet service covering all existing and future Touch ‘n Go products & services, with the Slogan “Shaping the future of e-payments for Malaysians”. Payment Method : QR Code Transfer to Friends : Yes, with Phone Number Top Up Method : FPX, Credit or Debit Card, Reload Pin, or Auto Reload Merchants : Over 100K Merchants as at
    Read more

    FLCCC I-Recover Protocol: Post Vaccine Treatment Protocol (2023)

    -
    Image
    Although no official definition exists for post-COVID-vaccine syndrome, a temporal correlation between a patient receiving a COVID-19 vaccine and beginning or worsening of clinical manifestations is sufficient to diagnose as a COVID-19 vaccine-induced injury, when the symptoms are unexplained by other concurrent causes. Note that there are significant overlaps between the symptoms and features of long COVID/ long-hauler syndrome  and post-vaccine syndrome. However, a number of clinical features appear to be characteristic of post-vaccine syndrome; most notably, severe neurological symptoms appear to be more common following vaccination. To complicate matters further, patients with long COVID are often also vaccinated, making the issue of definition more difficult. Since there are no published reports detailing the management of vaccine-injured patients, the FLCCC treatment approach is based on the postulated pathogenetic mechanism, clinical observation, and patient anecdotes. Treatment
    Read more

    Best 7 Executive MBAs in Malaysia 2022

    -
    Image
    Executive MBA programs are designed for working executives, managers, entrepreneurs, and other business leaders who have many years of work experience, to gain an MBA whilst still working for their companies. Courses are typically explored from a management perspective and are often scheduled at night and on the weekends to accommodate working professionals. Below is a list of executive MBA programs in Malaysia. We have gone beyond and shortlisted a list of top 7 recommended MBA programs so that it's easier for you to choose. The list is based on Google Search Results and information available on blogs, reviews sites and forums. The recommended MBA programs have been arranged in no particular order. Check out the list below. #1. Master of Business Administration Open University Malaysia The MBA programme is designed to enhance student's managerial skills and capability in managing organisations efficiently and effectively. The OUM MBA provides the opportunity for th
    Read more