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RSV Vaccine 2023: Moderna Granted FDA Breakthrough Therapy Designation for mRNA-1345

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Designation based on positive topline data from the ConquerRSV Phase 3 pivotal efficacy trial, which demonstrated vaccine efficacy of 83.7% against RSV lower respiratory tract disease, defined by 2 or more symptoms in older adults CAMBRIDGE, MA / ACCESSWIRE / January 30, 2023 /  Moderna, Inc. (NASDAQ:MRNA), a biotechnology company pioneering messenger RNA (mRNA) therapeutics and vaccines, today announced mRNA-1345, an investigational mRNA vaccine candidate for respiratory syncytial virus (RSV), has been granted Breakthrough Therapy Designation by the U.S. Food and Drug Administration (FDA) for the prevention of RSV-associated lower respiratory tract disease (RSV-LRTD) in adults aged 60 years or older. The designation was based on  positive topline data  from the ConquerRSV Phase 3 pivotal efficacy trial. "The FDA's Breakthrough Designation for mRNA-1345 further emphasizes the significant health impact of RSV in older adults and the high unmet need," said Stéphane Bancel, ...

Fenbendazole Dosage for Human Cancer

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Many people with cancer are seeking alternative therapies. One such therapy that has recently emerged is the  Fenbendazole protocol,   following some inspiring   fenbendazole cancer success stories . Fenbendazole (also called fenben) is a veterinary medicine used to treat worms and parasites in animals. It is often sold under the brand names Safe-Guard and Pancur.   Is fenbendazole safe for humans? Although fenbendazole hasn’t been studied in human cancer patients, there has been a lot of research on how it can benefit other conditions. As a result, it is generally considered safe for human use. ( Mebendazole  – which mainly treats human parasites, is from the same family of drugs). Fenbendazole has not received approval from the Food and Drug Administration (FDA). However, many cancer patients report positive effects from taking the medication and following the  Fenbendazole protocol to treat cancer .   Fenbendazole Dosage for Humans Getting the prope...

Eggs May Hold the Key to a New COVID-19 Treatment

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Multiple studies published in the last two years indicate that eggs from chickens immunized against   SARS-CoV-2   could be used to create effective treatments against   COVID-19   in humans. There is no evidence, however, that this development is responsible for the current egg shortage in the United States, as some conspiracy theories allege. In  a study published  in the Journal of Applied Microbiology March 2022, researchers found that egg  antibodies  (IgYs) produced by chickens immunized against the SARS-CoV-2 spike protein had the ability to neutralize the virus, specifically by interfering with the spike protein’s capacity to attach to human cells. The researchers concluded that IgY targeting the spike protein “could be a promising candidate for pre- and post-exposure prophylaxis or treatment of COVID-19.” They added that “administration of IgY-based oral preparation, oral or nasal spray may have profound implications for blocking SARS-CoV...

PFAS Are in Every Bite of Freshwater-Caught Fish

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Once a healthy mainstay of native diets, freshwater fish in the U.S. have been rendered toxic by environmental pollutants. Even eating one fish a year could be dangerous, due to the high levels of per- and polyfluoroalkyl substances, or PFAS, they contain. The research, conducted by scientists with the Environmental Working Group (EWG), revealed that consuming a single serving of freshwater fish annually equates to a month of drinking water contaminated with PFOS — one type of PFAS — at a concentration of 48 parts per trillion. Given that people in many vulnerable U.S. communities still depend on freshwater fish as a key part of their diets, public health could be at risk. “These test results are breathtaking,” Scott Faber, EWG’s senior vice president for government affairs, said in a news release. “Eating one bass is equivalent to drinking PFOS-tainted water for a month.” 1 Freshwater Fish Turned Toxic For the study, EWG researchers analyzed data from more than 500 f...

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