Top 10 Drugs by Worldwide Sales in 2025
The pharmaceutical market in 2025 continues to be led by innovative therapies addressing cancer, metabolic diseases, autoimmune conditions, and chronic illnesses. Below is an updated overview of the top 10 drugs by projected global sales in 2025. Summary 1. Keytruda (Merck): 31B 2. Ozempic (Novo Nordisk): 21 B 3. Mounjaro (ELi Lilly): 19 B 4. Dupixent (Sanofi and Regeneron): 17 B 5. Wegovy (Novo Nordisk): 14.3 B 6. Biktarvy (Gilead Sciences): 13.4 B 7. Skyrizi (Abbvie): 13 B 8. Eliquis (Bristol-Myers Squibb): 13 B 9. Darzalex (Johnson & Johnson): 13 B 10. Humira (Abbvie): 12.5 B Highlights and Market Trends Keytruda (Pembrolizumab) remains the global leader in drug sales with projected revenues exceeding $31 billion in 2025. This cancer immunotherapy has expanded to over 40 approved indications since its launch in 2014, including multiple cancer types, driving strong sales growth. Merck reported $21.6 billion in sales for the first three quarters of 2024, an 18% increase year-on-ye...